What kind of medicine is Acitretin A capsule?
Acitretin capsules are a prescription drug used to treat severe psoriasis (such as erythrodermic psoriasis, pustular psoriasis) and other keratotic skin diseases. Its main ingredient is Acitretin, a retinoic acid drug that improves symptoms by regulating the growth and differentiation of skin cells. Below is detailed structured data and analysis about Acitretin Capsules.
1. Basic information about acitretin capsules
| Drug name | Acitretin capsules |
| common name | Acitretin |
| drug class | Retinoids |
| Indications | Severe psoriasis, keratodermatosis |
| Dosage form | capsule |
| Common specifications | 10mg/capsule, 25mg/capsule |
2. The mechanism of action of acitretin capsules
Acitretin A acid regulates the proliferation and differentiation of epidermal cells by binding to retinoic acid receptors, reducing abnormal keratinogenesis, thereby alleviating the symptoms of skin diseases such as psoriasis. Its specific functions include:
| function | Effect |
| Inhibit excessive proliferation of keratinocytes | Reduce skin thickening and scaling |
| Promote normal differentiation | Improve skin barrier function |
| anti-inflammatory effect | Reduce redness, swelling and itching |
3. Usage and dosage of acitretin capsules
Acitretin capsules must be used strictly according to the doctor's instructions. The following is the routine usage:
| crowd | Recommended dosage |
| adult | Initial dose 10-25mg/day, adjusted according to efficacy |
| elderly | Caution is required and dose reduction may be necessary |
| children | Not recommended (safety not clear) |
4. Side effects and contraindications of acitretin capsules
Acitretin capsules may cause the following adverse reactions and require close monitoring:
| Common side effects | serious side effects |
| Dry, flaky skin | abnormal liver function |
| Cheilitis, dry mouth | Elevated blood lipids |
| light sensitive | Teratogenic risk (contraindicated for pregnant women) |
5. Medication precautions
1.Not allowed for pregnant women: Acitretin has clear teratogenicity, and strict contraception is required during medication and within 2 years after discontinuation of medication.
2.Regular inspection: Liver function, blood lipids and bone changes need to be monitored.
3.Avoid combined medications: It is prohibited to take it with tetracyclines, methotrexate and other drugs.
4.sun protection: Avoid sun exposure while taking this medicine.
6. Comparison between acitretin capsules and other drugs
| medicine | Advantages | Disadvantages |
| Acitretin capsules | Effective for refractory psoriasis | Many side effects require long-term monitoring |
| Biologics (such as adalimumab) | Targeted therapy with fewer side effects | expensive |
| topical corticosteroids | Quick onset of effect | Long-term use can easily lead to skin atrophy |
7. Answers to Frequently Asked Questions by Patients
Q: How long do I need to take Acitretin capsules?
A: The course of treatment is usually 3-6 months and needs to be adjusted according to the condition.
Q: How long does it take for the medicine to take effect?
A: It usually starts to take effect in 2-4 weeks, and complete relief may take several months.
Q: What should I do if I miss a dose?
A: If you miss a dose, there is no need to make up for it. Take the medicine as originally planned next time.
Summary
Acitretin capsules are an important drug for the treatment of severe psoriasis, but you need to strictly follow the doctor's instructions and pay attention to side effects monitoring. Patients should undergo regular follow-up visits during medication and adopt a healthy lifestyle to improve efficacy.
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